Effect of Kelatin on Diabetes 2: A Double-Blind Clinical Trial
Abstract
Background: Diabetes is a chronic metabolic disease characterized by high blood glucose levels. It can be treated through diet, physical activity, and medication. Insulin and antidiabetic medications are commonly used, but alternative treatments such as medicinal plants have also been studied. kelatin with the scientific name of Glaucium flavum has chemical compounds of this plant including phytol, tricosan, 2-pentadecanone, and henicosan. As a result, sesquiterpene hydrocarbons were shown as the main group of the essential oils of the species. This study sought to determine the effects of Hydroalcoholic Extract Kelatin (Glaucium flavum) on Type 2 Diabetes.
Method: This is a randomized controlled clinical trial in which 66 diabetic patients were randomly divided into two groups. The experimental group patients received kelatin capsules for 60 days. Patients in control group received placebo capsules containing starch. Fasting blood sugar (FBS), hemoglobin A1c (HbA1c), insulin, high-density lipoprotein (HDL), low-density lipoprotein (LDL), Triglyceride, Cholesterol, Creatinine and Urea were measured before and after study
Results: The results of study show that, despite a significant decrease in FBS, HbA1c,Triglyceride, Cholesterol, HDL and Creatinine level before and after the study in experimental group, there were no significant difference in most variables between experimental and control group after intervention .
Conclusion: In this study there was no significant difference in most variables after intervention. This result could be due to small sample size.
Keywords: Kelatin, Glaucium flavum; Type 2 diabetes, Persian Traditional Medicine, Herbal Medicine
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DOI: http://dx.doi.org/10.62940/als.v12i3.3274
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