Employment of the laser-induced breakdown spectroscopy (LIBS) technique for the diagnosis of renal failure in patients with (Fe) deficiency

Iman Sami, Muayyed Jabar Zoory, Sadiq Hassan Lefta

Abstract


Background: Iron deficiency is known to have implications for kidney function, and its association with renal failure has prompted investigations into novel diagnostic tools. This study explores the potential of Laser Breakdown Spectroscopy (LIBS) as a diagnostic technique for identifying renal failure in iron-deficient patients.

Methods: Blood samples from patients with renal failure and iron deficiency were subjected to LIBS analysis, with results compared to samples from healthy individuals. LIBS involves directing a high-energy laser onto the sample, generating plasma that emits distinctive spectral lines. The elemental composition of the sample can be determined by analyzing these lines.

Results: Statistically significant differences in the initial composition of blood samples were observed between patients with renal failure and iron deficiency, as opposed to those from healthy individuals. Specific elemental markers indicative of renal failure in iron-deficient patients were identified through LIBS analysis.

Conclusion: This study suggests that LIBS holds promise as a cost-effective and efficient diagnostic tool for detecting renal failure in iron-deficient patients. The identification of specific elemental markers offers potential for targeted diagnostic interventions, emphasizing the clinical utility of LIBS in the realm of renal health assessment.

Keywords: Plasma; Blood Minerals; Patients with Chronic Renal Failure; Iron Element  


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DOI: http://dx.doi.org/10.62940/als.v11i1.1962

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