A Study on the Role of Folic Acid and Vitamin D in Pregnant Women with Threatened Abortion

Raid M. H. Al-Salih, Shaimaa Dohie

Abstract


Background: Concentrations of progesterone, folic acid, malondialdehyde (MDA), vitamin D (VD), and ceruloplasmin (Cp) are very important indicators of abortion in pregnant women. Thus, the measurement of correlations between these indicators is very much required for the better understanding of the cause and the pattern of abortion in pregnant women.

Methods: Four groups were analyzed for the serum content of folic acid, Vitamin D (VD), progesterone, MDA, and Cp: 25 patients with threatened abortion, 25 patients with inevitable abortion, 25 pregnant women with regular status of pregnancy, and 25 healthy non-pregnant women.

Result: In the threatened abortion group, levels of folic acid were considerably lower than in the other groups. Levels of VD also declined in the threatened abortion group, but its level is highest in non-pregnant healthy women. Levels of progesterone were higher in the healthy pregnant women, followed by the threatened abortion group, and lowest in the abortion group. Levels of MDA and Cp were elevated considerably in the threatened abortion group.

Conclusion: Deficiencies in folic acid and VD are strongly linked with complications during pregnancy. Adequate monitoring and supplementation are critical in the prevention of threatened abortion and the enhancement of pregnancy outcomes.

Keywords:Vitamin D, Pregnancy, Progesterone, Folic Acid, Threatened Abortion

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DOI: https://doi.org/10.62940/als.v13i1.2218

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