Correction: Impact of varying sorbitol concentrations on hematological and biochemical blood parameters in Wistar rats (Rattus norvegicus)

Abstract

This Correction refers to: Al-Moussawi ZHK, Almahdawi MKK, Al-Bayati ASS, (2024). Impact of varying sorbitol concentrations on hematological and biochemical blood parameters in Wistar rats (Rattus norvegicus). Advancements in Life Sciences, 11(4). https://doi.org/10.62940/als.v11i4.2220

Following an internal audit conducted after post‑publication quality concerns were raised, the Editorial Office has identified reference mismatches in the above article. The authors have confirmed the following corrections, none of which alter the experimental dataset, numerical results, tables, figures, statistical outcomes, or the principal conclusions of the study.

Reference corrections

• Ref. [2]: Replaced with new Ref. [2] (Zhang et al., 2020), below.
• Ref. [12]: The statement on sorbitol absorption, hepatic/muscular glycogen synthesis, and postprandial glucose spikes during pregnancy and lactation is now supported, alongside Ref. [11] (Yang et al.), by new Ref. [12] (Cardoso et al., 2016), below.
• Ref. [13]: The statement on intestinal malabsorption, colonic osmolality, and osmotic diarrhea following high‑dose sorbitol intake is now supported by new Ref. [13] (Hattori et al., 2021), below, in place of the original citation.
• Ref. [15]: The statement on sorbitol‑related metabolic disturbance in diabetic subjects is revised and now supported by new Ref. [15] (Schmidt et al., 2005), below.
• Refs. [16, 17]: The statement on sorbitol's role in osmotic cellular stress rather than as a pregnancy stimulant is revised and now supported by new Refs. [16] (de Mendonça et al., 2022) and [17] (Kobayashi et al., 2002), below.
• Ref. [18]: The statement on polyol‑pathway activation and its effect on renal glucose‑metabolite handling is now supported by new Ref. [18] (Iizuka, 2023), below.
• Ref. [28]: The statement on decreased plasma insulin and carbohydrate‑metabolism disturbances following high‑dose sorbitol is now supported by new Ref. [28] (Al‑Tamimi et al., 2021), below.

Corrected references

• [2]: Zhang W, Chen J, Chen Q, Wu H, Mu W. Sugar alcohols derived from lactose: lactitol, galactitol, and sorbitol. Applied Microbiology and Biotechnology, (2020); 104(22): 9487–9495.
• [12]: Cardoso FS, Araujo‑Lima CF, Aiub CAF, Felzenszwalb I. Exposure to sorbitol during lactation causes metabolic alterations and genotoxic effects in rat offspring. Toxicology Letters, (2016); 260: 36–45.
• [13]: Hattori K, Akiyama M, Seki N, Yakabe K, Hase K, Kim YG. Gut microbiota prevents sugar alcohol‑induced diarrhea. Nutrients, (2021); 13(6): 2029.
• [15]: Schmidt RE, Dorsey DA, Beaudet LN, Parvin CA, Yarasheski KE, Smith SR, Williamson JR, Peterson RG, Oates PJ. A potent sorbitol dehydrogenase inhibitor exacerbates sympathetic autonomic neuropathy in rats with streptozotocin‑induced diabetes. Experimental Neurology, (2005); 192(2): 407–419.
• [16]: de Mendonça EL, Fragoso MB, de Oliveira JM, Xavier JA, Goulart MO, de Oliveira AC. Gestational diabetes mellitus: the crosslink among inflammation, nitroxidative stress, intestinal microbiota and alternative therapies. Antioxidants, (2022); 11(1): 129.
• [17]: Kobayashi T, Kaneko T, Iuchi Y, Matsuki S, Takahashi M, et al. Localization and physiological implication of aldose reductase and sorbitol dehydrogenase in reproductive tracts and spermatozoa of male rats. Journal of Andrology, (2002); 23(5): 674–684.
• [18]: Iizuka K. Recent progress on fructose metabolism ChREBP, fructolysis, and polyol pathway. Nutrients, (2023); 15(7): 1778.
• [28]: Al‑Tamimi MJ, Kassab RY, Othman SA. Biochemical and hormonal alterations associated with polyol consumption in Wistar rats. Journal of Applied Pharmaceutical Science, (2021); 11(8): 112–119.

These corrections do not affect the study's data, results, or conclusions. The Editorial Office apologizes for these errors and thanks the authors for their prompt cooperation in resolving them.

Correction Published

20 October 2026: The necessary corrections have been carried out in the Version of Record.