3D-Bioprinting: A stepping stone towards enhanced medical approaches

Hajra Ashraf, Bisma Meer, Romasa Naz, Aarooj Saeed, Haleema sadia, Usmara Sajid, Kanwal Nisar, Zuniara Aslam, Pervez Anwar

Abstract


In the past few decades, tissue engineering has been seen unprecedented escalation driving the field of artificial tissue and organ construct and brought metamorphosis in regenerative medicine. Prime advancement has been attained through the expansion of novel biomanufacturing approaches to devise and convene cells in three dimensions to fabricate tissue contrive. Accompaniment manufacturing differently known as 3D bioprinting is leading prime innovation in a number of applications in life sciences such as tissue and organ construct, personalized drug dosing, cancer model and heart tissue engineering. Overall, this review summarizes most prevalent bioprinting technologies; including laser-based bioprinting, extrusion bioprinting, injection bioprinting, stereolithography as well as biomaterial such as bioink. It also explores 3D industries, approaches such as Biomimicry, autonomous self-assembly, mini tissues and biomedical applications. Existing challenges that impede clinical mileage of bioprinting are also discussed along with future prospective.

Keywords: Bioprinting, tissue engineering, tissue and organ construct, medicinal approach


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