Hyperhomocysteinemia: The independent risk factor of cardiovascular diseases
Abstract
Hyperhomocysteinemia (Hcy) is an independent risk factor for cardiovascular diseases (CVD) and associated with primary causes of mortality and morbidity throughout the world. Association between Hcy and CVD has been a question for biologists over the last five decades. The circulating levels of Hcy can be increased by defects in enzymes involved in the metabolism of several B and therefore for homocysteine. Although researchers have yielded conflicting findings on the link between homocysteine and CVD risk, but there is convincing evidence on link between B vitamin deficiencies and increased CVD risk. This review identifies the research conducted on this subject matter and provides a framework for the factors associated with Hcy and CVD.
Keywords: Hyperhomocysteinemia; CVD; Methionine; Homocysteine
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