Public COVID-19 vaccination acceptance: A narrative review of correlated factors

Amirali Hatami, Ahmad Hajiloo, Romina Bayati, Peyman Kakavand, Amir Hossein Nasrollahi, Amir Hossein Yarahmadi, Mohammad Javad Nourmohammadi, Heshmatollah Asadi

Abstract


Following the discovery of the first instances of COVID-19 in nations and the subsequent announcement of a “pandemic” by WHO, worldwide efforts to identify efficient methods to combat COVID-19 began. One of the most effective solutions is to carry out widespread vaccination against the virus. Despite this, some members of the community refuse to be vaccinated. The present paper reviews the potential causes and factors correlating with people's hesitation to receive COVID-19 vaccines. This article is a narrative review paper. We searched PubMed, Scopus, and Web of Science databases using COVID-19, Vaccine, Acceptance, and Hesitancy keywords. Qualitative content analysis was performed and associated predictors with public vaccination acceptance were identified. According to the study,  hesitation in receiving COVID-19 vaccines, regardless of the countries, is significant among females, lower ages, lower education level, doubt about efficacy, and concerns about the safety of the vaccines, history of not receiving vaccines, especially the influenza vaccine, distrust of regional or national health officials, low level of health literacy and lack of information, fear of side effects and other complications, doubt of pharmaceutical companies and fear of lobbying, presence of chronic underlying diseases and comorbidities, lower socioeconomic status and racial or religious minorities. According to the results, several factors can influence individuals' uncertainty about COVID-19 vaccines. Given the importance of vaccinating the majority of the community to achieve mass immunity, healthcare systems should consider the vaccine acceptance rate to be a vital and substantial factor.

Keywords: COVID-19; Vaccination Refusal; Review 


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Lotfi M, Hamblin MR, Rezaei N. COVID-19: Transmission, prevention, and potential therapeutic opportunities. Clinica chimica acta; international journal of clinical chemistry, (2020); 508: 254–66.

Acuti Martellucci C, Flacco ME, Cappadona R, Bravi F, Mantovani L, Manzoli L. SARS-CoV-2 pandemic: An overview. Advances in biological regulation, (2020); 77: 100736.

Chen J, Wang R, Wang M, Wei GW. Mutations Strengthened SARS-CoV-2 Infectivity. Journal of molecular biology, (2020): 4; 432(19): 5212–26.

Cucinotta D, Vanelli M, WHO Declares COVID-19 a Pandemic. Acta Biomed: Atenei Parmensis, (2020); 91(1): 157–60.

Borriello A, Master D, Pellegrini A, Rose JM. Preferences for a COVID-19 vaccine in Australia. Vaccine, (2021); 39(3): 473–9.

Lazarus JV, Ratzan SC, Palayew A, Gostin LO, Larson HJ. A global survey of potential acceptance of a COVID-19 vaccine. Nature medicine, (2021); 27(2): 225–8.

McClung N, Chamberland M, Kinlaw K, Bowen Matthew D, Wallace M. The Advisory Committee on Immunization Practices’ Ethical Principles for Allocating Initial Supplies of COVID-19 Vaccine – United States, 2020. MMWR Morbidity and mortality weekly report, (2020); 69(47): 1782–6.

Fisher KA, Bloomstone SJ, Walder J, Crawford S, Fouayzi H. Attitudes Toward a Potential SARS-CoV-2 Vaccine : A Survey of U.S. Adults. Annals of internal medicine, (2020); 173(12): 964–73.

Guay M, Gosselin V, Petit G, Baron G, Gagneur A. Determinants of vaccine hesitancy in Quebec: a large population-based survey. Human vaccines & immunotherapeutics, (2019); 15(11): 2527–33.

Hildreth JEK, Alcendor DJ. Targeting COVID-19 Vaccine Hesitancy in Minority Populations in the US: Implications for Herd Immunity. Vaccines, (2021); 9(5): 489.

Yang W. Transmission dynamics of and insights from the 2018-2019 measles outbreak in New York City: A modeling study. Science advances, (2020); 6(22): eaaz4037.

Lo NC, Hotez PJ. Public Health and Economic Consequences of Vaccine Hesitancy for Measles in the United States. JAMA pediatrics, (2017); 171(9): 887–92.

Akiful Haque MM, Rahman ML, Hossian M, Matin KF, Nabi MH. Acceptance of COVID-19 vaccine and its determinants: evidence from a large sample study in Bangladesh. Heliyon, 2021;7(6): e07376.

Ranpariya VK, Hrin ML, Maghen P, Feldman SR. Assessing behavioral economic-based approaches to address covid-19 vaccine hesitancy. Journal of Ambulatory Care Management, (2021); 44(4): 336–41.

ES, JW, MD L, BM B, MB. Correlates of COVID-19 vaccine hesitancy in Austria: trust and the government. Journal of public health (Oxford, England), (2021): 44(1): e106-e116.

RO, TY, SO, TM, TT. COVID-19 Vaccine Hesitancy and Its Associated Factors in Japan. Vaccines, (2021); 9(6): 662.

AA M, SM M, J E, SB O. Determinants of COVID-19 vaccine acceptance in the US. EClinicalMedicine, (2020); 26: 100495.

Navarre C, Roy P, Ledochowski S, Fabre M, Esparcieux A, et al. Determinants of COVID-19 vaccine hesitancy in French hospitals. Infectious Diseases Now, (2021); 51(8): 647-653.

Bono SA, Faria de Moura Villela E, Siau CS, Chen WS, Pengpid S, et al. Factors affecting COVID-19 vaccine acceptance: an international survey among low-and middle-income countries. Vaccines, (2021); 9(5): 515.

Arvanitis M, Opsasnick L, O’Conor R, Curtis LM, Vuyyuru C. Factors associated with COVID-19 vaccine trust and hesitancy among adults with chronic conditions. Preventive Medicine Reports, (2021): 10(14); 84-89.

Liu D, Luo L, Xie F, Yu Z, Ma ZF. Factors associated with the willingness and acceptance of SARS-CoV-2 vaccine from adult subjects in China. Human Vaccines and Immunotherapeutics, (2021); 17(8): 2405–14.

Smith-Norowitz TA, Silverberg JI, Norowitz EM, Kohlhoff S, Hammerschlag MR. Factors impacting vaccine hesitancy toward Coronavirus disease-19 (COVID-19) vaccination in Brooklyn, New York. Human Vaccines and Immunotherapeutics, (2021); 20(10): 1–2.

Freeman D, Lambe S, Yu LM, Freeman J, Chadwick A, et al. Injection fears and COVID-19 vaccine hesitancy. Psychological medicine, (2021): 11; 1-11.

Saban M, Myers V, Shetrit SB, Wilf-Miron R. Issues surrounding incentives and penalties for COVID-19 vaccination: The Israeli experience. Preventive medicine, (2021); 153106763.

Štěpánek L, Janošíková M, Nakládalová M, Štěpánek L, Boriková A, et al. Motivation to COVID-19 vaccination and reasons for hesitancy in employees of a Czech tertiary care hospital: A cross-sectional survey. Vaccines, (2021); 9(8): 863.

de Oliveira BLCA, Campos MAG, Queiroz RCDS, Alves MTSSDBE, de Souza BF. Prevalence and factors associated with covid-19 vaccine hesitancy in Maranhão, Brazil. Revista de Saude Publica, (2021); 55: 1–12.

Nazlı ŞB, Yığman F, Sevindik M, Deniz Özturan D. Psychological factors affecting COVID-19 vaccine hesitancy. Irish Journal of Medical Science, (2022); 191(1): 71-80.

Wong LP, Alias H, Danaee M, Ahmed J, Lachyan A. COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries. Infectious Diseases of Poverty, (2021); 10(1): 1–14.

1. Faturohman T, Kengsiswoyo GAN, Harapan H, Zailani S, Rahadi RA, et al. Factors influencing COVID-19 vaccine acceptance in Indonesia: an adoption of Technology Acceptance Model. F1000Research, (2021); 10: 1-23.

Wang J, Jing R, Lai X, Zhang H, Lyu Y, et al. Acceptance of COVID-19 Vaccination during the COVID-19 Pandemic in China. Vaccines, (2020); 8(3): 482.

Chan WL, Ho YHT, Wong CKH, Choi HCW, Lam KO, et al. Acceptance of COVID-19 vaccination in cancer patients in Hong Kong: approaches to improve the vaccination rate. Vaccines, (2021); 9(7): 792.

Al-Qerem WA, Jarab AS. COVID-19 vaccination acceptance and its associated factors among a Middle Eastern population. Frontiers in public health, (2021); 9632914.

Sadaqat W, Habib S, Tauseef A, Akhtar S, Hayat M. Determination of COVID-19 Vaccine Hesitancy Among University Students. Cureus, 2021; 13(8): e17283.

Yahia AIO, Alshahrani AM, Alsulmi WGH, Alqarni MMM, Abdulrahim TK. Determinants of COVID-19 vaccine acceptance and hesitancy: a cross-sectional study in Saudi Arabia. Human Vaccines and Immunotherapeutics, (2021); 16(10): 1–6.

Riccio M del, Boccalini S, Rigon L, Biamonte MA, Albora G. Factors influencing sars-cov-2 vaccine acceptance and hesitancy in a population-based sample in Italy. Vaccines, (2021); 9(6): 1–10.

Sallam M, Dababseh D, Eid H, Al-Mahzoum K, Al-Haidar A. High rates of covid-19 vaccine hesitancy and its association with conspiracy beliefs: A study in jordan and kuwait among other arab countries. Vaccines, (2021); 9(1): 1–16.

Shacham M, Greenblatt-Kimron L, Hamama-Raz Y, Martin LR, Peleg O, et al. Increased COVID-19 vaccination hesitancy and health awareness amid COVID-19 vaccinations programs in Israel. International journal of environmental research and public health, (2021); 18(7): 3804.

Duong TV, Lin C-Y, Chen S-C, Huang Y-K, Okan O, et al. Oxford COVID-19 vaccine hesitancy in school principals: impacts of gender, well-being, and coronavirus-related health literacy. Vaccines, (2021); 9(9): 985.

Savoia E, Piltch-Loeb R, Goldberg B, Miller-Idriss C, Hughes B, et al. Predictors of COVID-19 vaccine hesitancy: socio-demographics, co-morbidity, and past experience of racial discrimination. Vaccines, (2021); 9(7): 767.

Riad A, Pokorná A, Antalová N, Krobot M, Zviadadze N. Prevalence and drivers of COVID-19 vaccine hesitancy among Czech university students: National cross-sectional study. Vaccines, 2021; 9(9): 1–25.

Taylor S, Landry CA, Paluszek MM, Groenewoud R, Rachor GS, et al. A proactive approach for managing COVID-19: the importance of understanding the motivational roots of vaccination hesitancy for SARS-CoV2. Frontiers in psychology, (2020); 11575950.

Piltch-Loeb R, Savoia E, Goldberg B, Hughes B, Verhey T, et al. Examining the effect of information channel on COVID-19 vaccine acceptance. Plos one, (2021); 16(5): e0251095.

Richardson A. Understanding Drivers of COVID-19 Vaccine Hesitancy Among Blacks. Biomedgerontology, (2020); (631): 1–10.

Mesele M. COVID-19 vaccination acceptance and its associated factors in Sodo Town, Wolaita Zone, Southern Ethiopia: cross-sectional study. Infection and Drug Resistance, (2021); 142361.

Chaudhary FA, Ahmad B, Khalid MD, Fazal A, Javaid MM. Factors influencing COVID-19 vaccine hesitancy and acceptance among the Pakistani population. Human Vaccines and Immunotherapeutics, (2021); 17(10): 3365–70.

Nasr L, Saleh N, Hleyhel M, El-Outa A, Noujeim Z. Acceptance of COVID-19 vaccination and its determinants among Lebanese dentists: a cross-sectional study. BMC Oral Health, (2021); 21(1): 1–10.

1. Mejri N, Berrazega Y, Ouertani E, Rachdi H, Bohli M, et al. Understanding COVID-19 vaccine hesitancy and resistance: another challenge in cancer patients. Supportive Care in Cancer, (2022); 30(1): 289-293.

Kaplan RM, Milstein A. Influence of a COVID-19 vaccine’s effectiveness and safety profile on vaccination acceptance. Proceedings of the National Academy of Sciences of the United States of America, 2021; 118(10): e2021726118.

Mussavi M, Asadollahi K, Janbaz F, Mansoori E, Abbasi N. The evaluation of red reflex sensitivity and specificity test among neonates in different conditions. Iranian Journal of Pediatrics, (2014); 24(6): 697-702.

Ma D, Han T, Karimian M, Abbasi N, Ghaneialvar H. Immobilized Ag NPs on chitosan-biguanidine coated magnetic nanoparticles for synthesis of propargylamines and treatment of human lung cancer. International Journal of Biological Macromolecules, (2020); 165: 767-775.

Karimi E, Abbasi S, Abbasi N. Thymol polymeric nanoparticle synthesis and its effects on the toxicity of high glucose on OEC cells: Involvement of growth factors and integrin-linked kinase. Drug Design, Development and Therapy, (2019); 13: 2513-2532.

Lahav, E, Rosenboim, M, Shahrabani, S, Song Y. Optimism and precautionary measures during the COVID-19 outbreak in China. American Journal of Health Behavior, (2021); 45(6): 978-992.

Quiroz-Gomez S, Guzman-Moreno M, Miranda-De LCA, Garcia-Hernandez, JM. Knowledge, Attitudes, and Practices toward the COVID-19 Pandemic in Tabasco, México. American Journal of Health Behavior, (2022); 46(1): 29-38.

Serpa ALO, Miranda DS, Costa JJ, Paula P, Mayra IC. Brief Symptom Inventory: Reporting Brazilian populational Parameters During COVID-19 Pandemics. Archives of Clinical Psychiatry, (2021), 48(1): 12-15.

Cooper JA, vanDellen M, Bhutani S. Self-weighing Practices and Associated Health Behaviors during COVID-19. American Journal of Health Behavior, (2021); 45(1): 17-30.

Kandeel M, Park BK, Morsy MA, Venugopala, KN, Oh-hashi K. Virtual Screening and Inhibition of Middle East Respiratory Syndrome Coronavirus Replication by Targeting Papain-like Protease. Dr. Sulaiman Al Habib Medical Journal, (2021); 3(4): 179 – 187.

Onuka OI, Oroboghae OR. Covid-19 and Poverty Assessment in Nigeria – The Vulnerability Approach. Asian Development Policy Review, (2021); 9(3): 127–143.

Kiasalar M, Shokrkhah Y, Namazi H. Action Research: The National Festival of CORONAREVAYAT (Corona Narrative) in Iran; An Experience Report and Analysis. International Journal of Body, Mind and Culture, (2022); 9(2): 63-76.

Bendaif H, Hammouti B, Stiane I, Bendaif Y, Ouadi EI. Investigation of spread of novel coronavirus (COVID-19) pandemic in MOROCCO & estimated confinement duration to overcome the danger phase. Caspian Journal of Environmental Sciences, (2020); 18(2): 149-156.

Joharifard R, Nouri R, Hazrati S, Fekryan-Arani S. Effectiveness of Acceptance and Commitment Therapy on COVID-19 Induced Anxiety among Worried People. International Journal of Body, Mind and Culture, (2022); 9(2): 410-415.

Scheidt CE. Editorial: The COVID-19 Pandemia. International Journal of Body, Mind and Culture, 2021;8(2).

Monajemi A, Moghadam-Heidari G, Namazi H. Medical Humanities Reveals the Neglected Aspects of the Covid 19 Pandemic. International Journal of Body, Mind and Culture, (2021); 8(2): 85-92.

Abdulhameed NS, Ali R, Al-Dahhan H. Correlation of COVID-19 Receptors with Neutrophils and Their Role in the Adherence of Co-Infected Bacteria. Archives of Razi Institute, (2020); 77(2): 779-784.

Salih R, Mohamed N, Taha A. Genetic Sequence of Coronavirus Strains Isolated from Iraqi Patients and their Relationship with some Liver Enzymes and Interleukins. Archives of Razi Institute, (2022); 77(2): 809-819.

Karimi M, Gholami-Ahangaran M. A Brief Report on Current Evidence of Traditional Chinese Medicine in the Treatment of Patients Infected with SARS-CoV-2. Plant Biotechnology Persa, (2021); 3 (1): 34-36.

Halil K, Selcuk O, Mahmoud A. Changes in Symptoms and Severity of Obsessive Compulsive Disorder in Children and Adolescent Patients following the Covid-19 Pandemic. Archives of Clinical Psychiatry, (2021); 48: 83-9.

Hummig W, Cruz MM. Bruxism as a clinical indicator of mental ilness: lessons from the COVID-19 to the future!. Archives of Clinical Psychiatry (São Paulo), (2021); 48: 127-127.

Zhou J, Li Z, Meng H, Chang YC, Peng NH. Chinese Parental Awareness of Children's COVID-19 Protective Measures. American Journal of Health Behavior, (2021); 45(4): 657-664.


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